In conversations with global leaders in cardiology, we explore how our understanding of coronary artery disease is evolving — from anatomical stenosis to functional assessment, from reactive interventions to proactive prevention.

In this episode, Prof. Rasha Al-Lamee takes us inside the 2025 Lancet Commission’s radical rethinking of coronary artery disease — a shift that begins with how we define and detect atherosclerosis long before it becomes symptomatic. If you’re looking for what’s truly changing cardiovascular outcomes — this is where it starts.